Supergirl

Kara Zor-El, also known as Supergirl, hardened by trauma and tragedy, celebrates her 21st birthday far from Earth aboard a spaceship with Krypto, her loyal superdog. When a young alien girl named Ruthye Marye Knoll, whose father was brutally murdered, asks Supergirl for help in tracking down the killer, the two embark on a quest through distant worlds.