Anno 2019, thirty years after WWIIi. From the ashes of destroyed Tokyo rose Neo-Tokyo, a city on the verge of anarchy. Violent gangs and terrorists keep the city in a stranglehold; the corrupt government can only maintain authority with the help of the powerful military. Tetsuo and Kanedo are best friends since childhood. Together with friends, they are also one of the many motorcycle gangs plaguing the city. When Wanneer Tetsuo is kidnapped to serve as a guinea pig for a scientific experiment, they become entangled in one of the city's darkest secrets.